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Research showed that glucagon co-agonism increased hepatic fat oxidation and thermogenesis, providing an additional fat-loss mechanism distinct from appetite suppression alone
The key takeaway from human genetic and epigenetic data is that the NNMT axis is biologically active and relevant to human metabolism
Hydroxocobalamin, in particular, is retained in the body longer than cyanocobalamin, which can reduce the frequency of repeat injections
Additional benefits include metabolic enhancement without growth hormone side effects, no impact on blood glucose or insulin sensitivity, potential increases in energy expenditure through thermogenic mechanisms, and compatibility with athletic training and performance goals
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