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Notably, genes decreased by LPS and restored by semaglutide (Cluster 2) were enriched for lysosomal and vacuolar functions (BH-adjusted P 1% were discarded

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The formaldehyde-containing DMEM was removed and cells were washed 3 times with 20ml of ice-cold PBS supplemented with 1x complete protease inhibitor cocktail

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Conclusion Semaglutide and other GLP-1 agonist or GLP-1/GIP dual agonist medications have been increasingly prescribed by medical practitioners

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