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(2006a, b) demonstrated the role of Comano thermal water in the significant inhibition of intracellular TNF-alpha, resulting in the downregulation of IL-8 and IL-6 in keratinocytes, which ultimately led to the control of the abnormal differentiation of keratinocytes, opening ways to treat skin diseases with underlying abnormal differentiation of keratinocytes
Hassan, J
F.RamirezP
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