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Increased HIF-1 activity is also observed for other iron chelators, such as salicylaldehyde isonicotinoyl hydrazone (SIH) and deferiprone ( FIGURE 11 Among the DFO analogs are those where the DFO molecule has been attached to various high-molecular weight polymers, including cellulose, dextran, or hydroxyethyl starch

Again, this was very similar to GHRP-6 (ED50 = 3.9+/-1.4 nmol/kg and Emax = 74+/-7ng GH/ml plasma)

It is commonly used in oral products and has been studied in human trials

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