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While both are effective in helping patients lose weight by influencing gut hormones that control appetite and blood sugar, Mounjaro has demonstrated greater average weight loss in head-to-head clinical trials, with some users losing up to 25 pounds

Gromada, J., Holst, J

The medication is absorbed directly into the bloodstream from subcutaneous tissue, making the presence or absence of food in the stomach clinically irrelevant to drug pharmacokinetics

Some protocols suggest holding the liquid in the mouth for 30-60 seconds before swallowing to allow for some initial absorption through the buccal mucosa (the lining of the mouth)