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Pros: One of the most extensively studied healing peptides in animal and in vitro models, with a broad published mechanistic literature Reported to have a favorable short-term tolerability profile in the limited human data available, with side effects typically mild and self-limiting Available in both injectable and oral research formulations, offering flexibility for different use cases Cons: No completed Phase 2 or Phase 3 human clinical trials exist

doi:10.17925/ee.2018.14.1.24

247 Second, clinically-important subgroups could be identified a priori and evaluated for treatment responses

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