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You should be prepared to discuss family members with suspected or confirmed lipedema, age of onset of your symptoms, body parts affected, and whether weight loss helped reduce symptoms of lipedema
Metabolic issues: Feeling constantly cold, chills, or a low body temperature (signs of metabolic acidosis) Severe gastrointestinal changes: Persistent diarrhea, vomiting, or a total loss of appetite Systemic changes: Unexplained tiredness, a fever or other signs of infection, unusual bleeding, bruising, or long-term concerns like osteoporosis In general, higher doses of topiramate are associated with an increased risk of adverse reactions
Evidencia citada Meta-anlisis de 3 ECA (878 sujetos): 14.33% de peso corporal vs placebo, con reduccin de IMC, cintura, glucosa en ayunas, HbA1c y presin arterial, sin diferencia significativa en eventos adversos
