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12 Specifically, the p53 R175H mutation decreases the binding affinity of the DBD and Zn 2+ and promotes incorrect folding and inactivation of the p53 protein
Tone evens out
One randomized placebo-controlled trial that assessed the effect of oral lipoic acid supplementation in 58 patients diagnosed with metabolic syndrome, a condition characterized by abnormal glucose and lipid metabolism, showed that flow-mediated vasodilation improved by 44% with 300 mg/day of lipoic acid for four weeks (66)
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