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DSIP or vehicle was administered intranasally at a dosage of 120 g/kg (n a volume of 100 L/kg
These drugs enhance satiety signalling in the brain and slow gastric emptying which reduces appetite and help people achieve a clinically meaningful weight loss 1
Combinations of GLP-1 with other entero-pancreatic hormones with complementary actions and/or synergistic potential (such as glucose-dependent insulinotropic polypeptide (GIP), glucagon, and amylin) are under investigation to enhance the weight loss and cardiometabolic benefits of GLP-1 RA [21]
Sci Rep 15:2035
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