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By preserving GLP-1, DPP-4i enhances GLP-1-induced activities in these tissues (Fig
contraindicated in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2), pancreatitis (discontinue if suspected), gallbladder disease, and acute kidney injury secondary to dehydration from gastrointestinal side effects
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