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We found that the key driver of this inhibition is the level of reactive oxygen species (ROS)-dependent IDO1 activity, rather than IDO1 expression ( Figure 1 Beyond its role in immune evasion, the KP also supports cancer cell survival and proliferation by supplying essential metabolic intermediates
But losing 10-15% to freeze damage may be preferable to losing 70% to expiration at room temperature or refrigeration beyond 30 days
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