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Environmental Toxicology and Pharmacology
Glutathione, which is a potent antioxidant, is composed of 3 amino acids, including glutamic acid, glycine, and cysteine
Fritz KS, Petersen DR
But oxidation by cytochrome P450 enzymes is one of the most common forms of bioactivation, resulting in toxic drug metabolites that can bind to cellular macromolecules such as proteins, lipids, or DNA, initiating cellular damage, inflammation, or even carcinogenesis
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