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Additional areas of study include its selectivity within adipose-related pathways and its interaction with metabolic signaling processes in controlled laboratory models
These early changes are subtle but encouraging
In head-to-head trials, tirzepatide produced greater reductions in the measured endpoints: superior HbA1c and weight loss in SURPASS-2, and a 20.2% versus 13.7% body-weight reduction in SURMOUNT-5
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