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It carries risks of acute pancreatitis, gallbladder disease, and potential diabetic retinopathy complications with rapid improvement in blood glucose

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The rate of loss slowed somewhat in the later weeks as a new energy balance was approached, but the trajectory had not leveled off by week 48

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Quick Answer: Zepbound may cause emotional changes in some patients, and the FDA label includes warnings to monitor for depression and suicidal thoughts, though clinical trials have not established a definitive causal relationship

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