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Key themes were identified from participant feedback

This mode of action confirms what the experts have been saying for several years, namely that it is a reduction in calorie intake that remains the main means of losing weight (physical exercise has enormous health benefits, but does not have major effects on weight loss)

P.HollandM

We conducted a comprehensive literature search across databases, including PubMed and Web of Science, compiling data from clinical trials, case reports, and basic research studies published up to 2025, with a focus on the efficacy, safety, and mechanism of action of drugs such as liraglutide, semaglutide, and tirzepatide in patients with MC4R deficiency