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Losing muscle while losing fat means the metabolism slows more than it should, making weight maintenance harder after the medication is discontinued
Here's a concrete example: Sarah, on month three of tirzepatide, started experiencing severe fatigue despite losing 22 pounds
Candidates for Tirzepatide therapy typically include adults with a BMI of 30 kg/m or greater (obesity) or those with a BMI of 27 kg/m or higher who also have conditions such as high blood pressure, type 2 diabetes, elevated cholesterol, obstructive sleep apnea, or cardiovascular disease
Key Takeaways Calibrate is the more structured program: It emphasizes GLP-1 prescriptions, insurance navigation, 1:1 video coaching, curriculum, lab review, and long-term behavior change
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