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One of the common adverse events of the chronic use of Nabiximols is mouth ulcerations (due to the ethanol excipient)

Now it seems oral small-molecule GLP-1s also dial back eating for pleasure by engaging a brain reward circuit. Lorenzo Leggio, clinical director of NIHs National Institute on Drug Abuse, noted the importance of understanding the neural mechanisms as patient uptake increases

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Advertising and Consumer Perception The extensive advertising of these medications has led to increased patient requests, sometimes for uses that are not approved