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A study comparing Mounjaro vs Wegovy found that the average weight loss with tirzepatide was 20.2% compared to 13.7% with semaglutide after 72 weeks of treatment
EMR does have some limitations
This creates a powerful one-two punch: the medication works chemically to signal satiety, while the fiber adds a physical sense of fullness
That gap is small, which makes it hard to say definitively whether tirzepatide itself is causing headache or whether something else related to treatment is real trigger
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