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GSH is synthesized in two steps, both ATP-dependent processes, catalyzed by the enzymes GCL (glutamate-cysteine ligase, aka -glutamylcysteine synthetase) and glutathione synthetase, and is regenerated by six enzyme-catalyzed reactions, known as the -glutamyl cycle
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It has been shown to improve cognitive function and memory and help with conditions such as depression and anxiety
Nat Commun 8 , 14835 (2017)
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