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The GPX4 essential cofactor GSH not only plays an important role in ferroptosis, but GSH depletion also induces a significant increase in autophagy (146), whereas erythropoietin (EPO) was able to increase the level of total GSH, reduce ROS levels, and improve cell viability in SCs in the HG environment (147)
doi: 10.3390/cells12162099 30 MomtazmaneshSZare-ShahabadiARezaeiN
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