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In addition to classic Spitz nevi, which are recognized as benign proliferations, certain Spitz tumors demonstrate extensive pleomorphic features indistinguishable from melanoma and are termed Spitzoid melanoma
Rotate injection sites regularly (abdomen, thighs, upper arms) to minimize local irritation and prevent lipohypertrophy
Most clinical data involves native rhIGF-1 or IGF-1/IGFBP-3 complexes in disease states such as growth hormone insensitivity syndrome
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