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The virus directly damages host cellular structural proteins and membrane lipid structures, and triggers a cytokine storm leading to immune dysregulation and hyperinflammatory responses, collectively contributing to a range of clinical manifestations ( The diverse pathologies arising from SARS-CoV-2 infection of the reproductive system, while clinically heterogeneous, share a common regulatory axis in their underlying ferroptosis mechanisms, alongside tissue-specific variations
Another more comprehensive meta-analysis, which included 29 studies, indicated that the sensitivity and specificity reached 80% and 88%, respectively
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