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Notably, tirzepatide is a dual incretin receptor agonist that activates both the glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor, distinguishing it from other GLP-1-specific agonists
Birkmayer, W
Retatrutide simultaneously activates GLP-1, GIP, and glucagon receptors, distinguishing it from licensed agents such as semaglutide or tirzepatide
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