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Drugs and Procedures Subject to Restrictions: Blood Doping Local Anesthetics (under some conditions) Manipulation of Urine Samples Beta-2 Agonists permitted only by prescription and inhalation

Benton CB, Boddu PC, DiNardo C, Bose P, Wang F, Pemmaraju N, Devendra KC, Pierce S, Patel K, Konopleva M, Ravandi F, Garcia-Manero G, Kadia T, Cortes J, Kantarjian H, Andreeff M , and Verstovsek S

Transcriptional up-regulation of inhibitory PAS domain protein gene expression by hypoxia-inducible factor 1 (HIF-1): a negative feedback regulatory circuit in HIF-1-mediated signaling in hypoxic cells