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Overall, the therapy of metformin was associated with changes in the abundance of specific bacterial genera in the human gut microbiota, but the effects on gut microbiota diversity were variable, which highlights the need for further research to understand the potential mechanisms and clinical significance
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Its not clear what causes this or if it has any practical implications for treatment with tirzepatide
Linaclotide acts locally in the gastrointestinal tract with minimal systemic absorption, which contributes to its favourable safety profile
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