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Pre-clinical studies showed that anti-atherogenic effect of GLP-1 is independent of modulation of plasma lipid levels and depends on anti-inflammatory response
Eli Lilly and Company), a combination GIP and GLP-1 receptor agonist, was FDA approved in 2022 to treat T2D and in 2023 to treat obesity.3 GLP-1 receptor agonists are known to possess positive cardiovascular effects
Exclusion criteria included non-randomized studies, trials enrolling pediatric populations, and studies of less than 1,000 patients or less than 12 month follow up
Results reveal whether your peptide pathways favor GLP-1 sensitivity, metformin responsiveness, or combination therapy
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