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The FDA-approved titration protocol for prescription semaglutide (Ozempic, Wegovy) follows a specific progression: 0.25 mg weekly for 4 weeks, then 0.5 mg weekly, advancing to 1 mg, then 1.7 mg, and finally 2.4 mg depending on your response and tolerance
In the SELECT study, people taking Wegovy had about 20% fewer heart-related events (meaning roughly 2 fewer events for every 10 that would have occurred otherwise)
Neither vitamin E nor metformin was superior to placebo in achieving the primary outcome, whereas the resolution of NASH was significantly greater in the vitamin E group
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