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Protest against ozone depletion
In this review, we highlight the past and present progress in our understanding and development of treatments based on GLP-1/glucagon co-agonism
GLP-1 receptors are distributed widely in the pancreas (glucose-dependent insulin secretion and glucagon suppression), the hypothalamic satiety centers, the GI tract (slowed gastric emptying), and even cardiomyocytes which is why a single incretin pathway produces effects across so many organ systems
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