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A diferencia de muchos compuestos, su efecto se observa tanto en administracin sistmica como local, e incluso por va oral en algunos modelos, lo que se atribuye a su notable estabilidad frente a la degradacin enzimtica
Alpha Arbutin &
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Rather than canonically activating downstream proinflammatory cytokines, STING promotes autophagic degradation of GPX4, thereby triggering neuronal ferroptosis (Woo et al., 2024)
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