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Two active forms of GLP-1 are generated in the gut and brain: active GLP-1 (7-36) amide and active GLP-1 (7-37) non-amide 10
When semaglutide is introduced after gastric sleeve surgery, it provides supraphysiologic GLP-1 receptor activation that exceeds the endogenous incretin response generated by the altered anatomy
Dosing and Administration Administering a medication requires proper medical supervision
Contribution statement All authors were responsible for drafting the article and for critically revising it for substantial intellectual content
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