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Some patients report that their usual morning coffee becomes less tolerable during the first few weeks of semaglutide treatment, particularly following dose escalations

Nevertheless, in some instances a worsening of depressive symptoms may occur as a consequence of weight loss (well documented in series of bariatric surgery patients) and/or as a possible side effect of GLP-1 receptor agonist therapy. Before taking these drugs, make sure your healthcare provider knows about any mental health diagnoses or concerns you have and any medications you take

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Most patients (78.6% vs