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Curr Allergy Asthma Rep 14(1):404

Transgenic animals were generated by microinjection of 10 ng/l plasmid DNA and 90 ng/l Pttx3rfp plasmid as a coinjection marker unless otherwise noted

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Research Applications and Scientific Value DSIP continues to be studied in research settings and clinical trials by scientists who are looking to better understand and aid: Sleep onset mechanisms and sleep architecture Stress response pathways and HPA axis function Neuroendocrine communication and hormone regulation Circadian rhythm mechanisms Neuroprotection under various stress conditions Substance dependence and withdrawal mechanisms Safety Considerations of DSIP Despite decades of research and preclinical studies, DSIP is unapproved for human consumption