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Weight and waist circumference DXA scans Resting energy expenditure (indirect calorimetry) Handgrip strength (dominant hand, highest of 3 trials) Bioelectrical impedance (total and third-space water) Sarcopenia diagnosis (via appendicular skeletal muscle mass/body weight ratio + grip strength using European Working Group on Sarcopenia (EWGSOP2) guidelines) Dropouts 115 participants enrolled

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It was discovered in 1977 when researchers isolated it from the brains of rabbits during induced sleep