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From 1,309 bioactive molecules screened, the computer analysis selected GHK at 1 micromolar and securinine at 18 micromolar as the optimal agents capable of reversing expression of 54 gene sets overexpressed in malignant invasive colon cancer

AI-assisted tools (Claude, Anthropic) were used for automated parsing and extraction of eligibility criteria from clinical trial registry free-text fields, with subsequent expert curation and validation

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