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Dextran sodium sulfate (DSS) colitis was induced in 8-week-old co-housed WT and Gpx4 +/IEC mice using 3% DSS (MP Biomedicals, 02160110) given in drinking water ad libitum for five consecutive days followed by tap water for the rest of the experiment
Toxicity is extremely rare
Usage Cited in: J Lipid Res
Creatinine clearance (GFR) was calculated using the standard formula: 3.7 Liver function analysis To evaluate potential hepatotoxicity, serum levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) were quantified at the experimental endpoint using commercially available colorimetric assay kits (AST: ab263882, Abcam, USA
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