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With GLP-1 medications like semaglutide and tirzepatide making headlines, many Americans are still unclear on how these treatments work, what the FDA allows, and where to find safe information
The recommended starting dose in patients not currently treated with metformin is 100 mg sitagliptin and 1000 mg metformin HCl extended-release once daily, with gradual dose escalation recommended to reduce gastrointestinal side effects associated with metformin
While formal clinical guidelines await development, evidence-based principles can guide initial exploration
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