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that is, if 14 patients were treated for 4 years with metformin 850 mg t.d.s., one would develop vitamin B12 deficiency

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The FDA-approved dosing schedule for Wegovy is: Week 1-4: 0.25 mg dose once weekly for the first 4 weeks (starting dose)/ Week 5-8: 0.5 mg dose once weekly Week 9-12: 1 mg once weekly, if needed Week 13-16: 1.7 mg once weekly, if needed Week 17 and beyond: 1.7 mg or 2.4 mg (maximum dose) The initial dose of Ozempic is 0.25 mg, which is injected once weekly for the first 4 weeks

This can be done in-person, or by phone or video