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An increased metabolic rate can lead to more efficient burning of calories and fat, which is a key factor in weight loss

Treatment will be deemed to have failed in these patients, and they will be further studied and treated outside the trial according to normal clinical practice

13 C NMR (126 MHz, CDCl 3 ) 172.40 (C), 170.08 (C), 135.34 (d, J = 3.0 Hz, CH 3), 133.80 (d, J = 10.0 Hz, CH 6), 130.75 (d, J = 12.5 Hz, CH 6), 118.18 (d, J = 86.1 Hz, C 3), 38.97 (CH 2 ), 36.89 (CH 2 ), 36.64 (CH 2 ), 27.82 (CH 2 ), 27.56 (d, J = 16.7 Hz, CH 2 ), 22.96 (d, J = 50.4 Hz, CH 2 ), 22.11 (d, J = 4.1 Hz, CH 2 )

For some people, the change is pretty subtle, maybe just an even and glowing look