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Ethics statement The studies involving human participants were reviewed and approved by the Institutional Review Boards at American University and Georgetown University

Metformin therapy and risk of cancer in patients with type 2 diabetes: systematic review

Although sometimes used synonymously, these terms actually describe technically different methods: Whitening : Generally means to decrease overall melanin production to achieve a lighter skin tone Brightening: Tends to improve luminosity and decrease dullness without necessarily altering skin colour Lightening: Tends to address specific dark spots or hyperpigmentation rather than overall tone Dr

PMID: 19230029