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2006 Dec;291(6):E1290-4
It activates the GIP receptor with approximately equal potency to native GIP, but activates the GLP-1 receptor with roughly five times lower potency than native GLP-1
Still, they are also a result of mitochondrial dysfunction, which occurs when mitochondria lose the protection of GSH, free radicals attack the mitochondria, and cellular energy decreases.8 Autoimmune conditions like multiple sclerosis, Crohns disease, rheumatoid arthritis, diabetes, Lyme disease, heavy metal load, organotoxins, and more all have mitochondrial dysfunction, low levels of GSH, and profound fatigue
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