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Loss of p53 promotes DPP4NADPH oxidase 1 (NOX1) interactions, forming a NOX1DPP4 complex that mediates plasma membrane lipid peroxidation and triggers ferroptosis (78)
This comprehensive, multi-pathway approach is why many functional medicine practitioners consider this synergy a foundational element for patients learning how to live with long-term COVID
DiNicolantonio, Dietary Glycine Is Rate-Limiting for Glutathione Synthesis and May Have Broad Potential for Health Protection, Ochsner J
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