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Early clinical data suggests higher rates of gastrointestinal side effects overall, with both constipation and diarrhea being common, sometimes alternating in the same user
Benefits and harms of drug treatment for type 2 diabetes: systematic review and network meta-analysis of randomised controlled trials
Fiber supplementation must be introduced slowlyincreasing by 5 grams weeklyto minimize bloating and gas, which may be particularly problematic given semaglutide's effects on gastric emptying
In clinical trials for type 2 diabetes, Mounjaro produced weight loss of 9.5% to 12.5%
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