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A deficiency in magnesium following cisplatin injection reduces the expression of efflux transporters, leading to increased accumulation of cisplatin in tubular cells, thereby exacerbating the severity of AKI [95]
A meta-analysis of randomized controlled trials found that daily vitamin E supplementation equivalent to 25 to 536 mg/day of RRR --tocopherol for several years resulted in a significant, 10% reduction in the risk of ischemic stroke (five trials, 91,393 participants) and a nonsignificant trend towards an increased risk of hemorrhagic stroke (five trials, 100,748 participants) (120)
DEREK MUNRO: It must say no more than two a day, but I would say on a podcast, not more than one is what I would recommend
Kobayashi, T
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