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Vitamin B 3 (niacin) also seems to be a promising compound for safely enhancing myelin phagocytosis by microglia (Rawji et al., 2020)
However, if the branded manufacturers process patent is also a use patent or covers the specific crystalline form that appears in the drug product, the linkage becomes more complicated and can affect the generics ANDA strategy
While generally considered safe, the legality of DSIP varies by country
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