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R., Yamaguchi, Y., Coelho, S
GHK-Cu is the best-known copper peptide, studied for its role in skin repair and renewal
One potential mechanism is the Nrf2-ARE pathway, which induces a phase 2 detoxification response that promotes disruption of Nrf2-Keap protein interactions, translocation of Nrf2 to the nucleus, and regulation of target gene expression through the ARE, enhancing cellular defense against oxidative damage (Hu et al., 2004
The trial also included a 1-mg dose arm for CagriSema compared with same doses of semaglutide, cagrilintide and placebo
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