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Role of PTPN22 in type 1 diabetes and other autoimmune diseases

Daud Samsudewa, Fitra Aji Pamungkas, and Herdis Herdis assisted with the literature collection and data interpretation

However, most current studies rely solely on the EAE mouse model and the LPC-induced localized myelin loss model, which do not fully recapitulate the complex pathological features of MS, particularly its heterogeneity, disease progression, and clinical symptoms