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The primary competitive threat is the emergence of next-generation GLP-1 based therapies that could partially displace semaglutide
By combining GLP-1 receptor agonists with other agents, such as GIP or glucagon receptor agonists, researchers are achieving greater weight loss, improved glycemic control, and broader metabolic benefits
While there is no direct drug-drug interaction that prevents you from using these two together, they both affect your digestive system in ways that require a thoughtful approach
This is common practice, though theres no official guidance yet from the American Gastroenterological Association
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