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The FDA does not consider a drug product to be commercially available, however, if it has been discontinued and is no longer marketed, or if the drug appears on the FDA drug shortage list, such as Wegovy
Gpxs exist in multiple isoforms, with different cellular localization and different substrate specificity (15)
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In the case of the developed IGF-1 MSIA-SRM, the use of the MSIA tips in comparison to beads translated into a 10-fold lower limit of detection and a 20-fold LLOQ for an extraction method requiring less than 30 minutes
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