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The second mechanism involves the nuclear transcription factor NRF2 (nuclear factor erythroid 2-related factor 2), which governs the cell's antioxidant defense network
The SCALE (Satiety and Clinical Adiposity-Liraglutide Evidence in individuals with and without diabetes) phase 3b trials investigating efficacy and safety of liraglutide 3.0 mg as an adjunct to diet and lifestyle advice for weight management have recently been published with two estimands [7, 8]
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