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The WHO emphasizes the severe danger posed by these counterfeit products, which may look convincing but lack the safety and quality assurance of genuine medications
ETD of -2.94%), but the overall magnitude of weight loss was still less than what was reported in the STEP and SUSTAIN trials, where average weight reductions reached ranges of 5-15% (ETD of -2.6% to -12.5%) over a similar duration of treatment with high-dose GLP-1s
Wegovy (semaglutide 2.4 mg) and Zepbound (tirzepatide) are FDA-approved specifically for chronic weight management in adults with a BMI of 30 or higher, or 27 or higher with at least one weight-related condition such as high blood pressure, sleep apnea, or dyslipidemia
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